Job Description

Payroll Title:
SRA 2 NEX
Department:
MEDICINE/Gastroenterology
Salary Range
Commensurate with Experience
Worksite:
East Campus
Appointment Type:
Career
Appointment Percent:
100%
Union:
RX Contract
Total Openings:
1
Work Schedule:
Days, 8 hrs/day, Monday-Friday

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.

#115702 Staff Research Associate/Lab Manager

Extended Deadline: Wed 6/1/2022

For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy

UCSD Layoff from Career Appointment: Apply by 04/21/22 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 05/03/22. Eligible Special Selection clients should contact their Disability Counselor for assistance.

This position will remain open until a successful candidate has been identified.

DESCRIPTION

The UCSD School of Medicine is one of the nation’s most prestigious medical schools and a preeminent institution for education, biomedical research, and clinical care. The School of Medicine’s faculty of 1,400 physicians and researchers are consistently ranked in the top two nationally in research funding per faculty member. As a top-tier academic medical center, its role is to provide leadership in improving health through research, education and patient care. UC San Diego Health Sciences has long been at the forefront of "bench-to-bedside" research, transforming patient care through discovery and innovation leading to new drugs and technologies.

The Zarrinpar laboratory is located in the beautifully built Altman Clinical and Translational Research Institute (ACTRI) at UCSD. The laboratory environment consists of over 3500 ft2 of contiguous space and includes state of the art laboratory resources; benches, common equipment, tissue culture rooms, cold room, and procedure rooms. The lab is interested in the intersection of circadian biology, gut physiology, and the gut microbiome and how the three interact to cause obesity, diabetes, steatohepatitis, dyslipidemia, and other gut-mediated diseases. We investigate the development of pathology as a dynamic process in a basic science and translational setting.

Specifically, the Zarrinpar lab is interested in the reciprocal interaction between the luminal environment (both the gut microbiome and the content) and the gut and how the two maintain physiological homeostasis and contribute to disease. This research is performed primarily in animal models, with the potential to move into clinical populations.

Under the general supervision of Principal Investigator (PI), the incumbent will independently manage all aspects of the research laboratory and conduct independent research projects. Incumbent has dual functions in scientific research and laboratory management in a microbiome and metabolism lab. With the help of the incumbent, the laboratory will be able to study the effects of specific bacterial functions and to test whether functional manipulations of the gut microbiome can lead to therapeutic or diagnostic agents.

MINIMUM QUALIFICATIONS

  • Theoretical knowledge or Bachelor's degree in a biological life science or related discipline or equivalent education and experience.

  • Experience maintaining mouse colonies and genotyping mice for the lab including maintenance of transgenic lines and knowledge of humane methods of caring for lab animals. Sensitivity to the needs of laboratory animals in compliance to American Association for Accreditation of Laboratory Animal Care (AAALAC) standards.

  • Experience with phenotyping mice particularly for metabolic, circadian, behavioral, cancer, and/or immunological experiments, including ability to gavage, perform bleeds/necropsy, injections, anesthesia, glucose and insulin tolerance tests, and metabolic cage data collection.

  • Experience with molecular biology techniques (e.g., PCR, qRT-PCR, DNA/RNA purification, gel electrophoresis, protein isolation) with the ability to carry out a variety of technical procedures with minimal instruction or supervision.

  • Enthusiasm for learning and genuine interest in scientific research. Willingness and ability to learn new skills, research methods, and scientific principles. Ability to take direction, be detail-oriented and follow step-wise instruction.

  • Ability to work independently or collaboratively on a research project. Ability to maintain a high level of motivation to contribute to cutting-edge research, and seek and learn new experimental methods as required.

  • Successful, positive interpersonal oral and written communication skills using tact, diplomacy, discretion, and flexibility with diverse personalities and situations. Skill to interact effectively with faculty, academics, students, and staff including those of diverse ethnicity, culture, and foreign nationals.

  • Demonstrated ability to provide work direction to undergraduate student lab employees. Skill to train others in various lab techniques and procedures (safety precautions, preparation of media, dishwashing, equipment usage, laboratory maintenance, etc).

  • Knowledge of Material Safety Data Sheets (MSDS), hazard communication, and Injury and Illness Prevention Program; safety precautions including appropriate clothing and shoes, safe handling of chemicals, and use of protective items such as gloves and goggles.

  • Experience and skill with MS Office programs, Google Docs, file-making, spreadsheet, and graphics software; willingness and ability to update and increase PC skills and knowledge as needed.

PREFERRED QUALIFICATIONS

  • Experience in generating RNA and DNA libraries for next generation sequencing.
  • Experience in preparing multiplex immunoassays and using multiplex systems.
  • Experience working in gut microbiome experiments including with germ-free mice.
  • Experience with gel electrophoresis and protein isolation.
  • Familiarity with handling BSL-2 bacteria, mammalian cell culture, and sterile technique.
  • Knowledge of UC San Diego Health purchasing procedures.
  • Experience with immunohistochemistry, staining, microscopy, and preparing tissue for histology.
  • Basic knowledge and experience of accounting, billing practices, purchasing and reimbursement procedures. Ability to proactively and appropriately facilitate the maintenance of all lab supplies and equipment, maintain steady levels of lab supplies, and organize purchasing records.

SPECIAL CONDITIONS

  • Employment is subject to a criminal background check.
  • Must be willing to work with mice as an experimental model.
  • Must be willing to work occasional evenings and weekends (for circadian experiments).
  • Must be willing to work with biohazardous material including bacteria and samples from mice and humans.

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

Application Instructions

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