Job Description

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Commensurate with Experience
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Days, 8 hrs/day, Monday-Friday

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.

#114267 Sr. Bioinformatics Scientist-Project Manager

Extended Deadline: Mon 5/30/2022

For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy

UCSD Layoff from Career Appointment: Apply by 02/02/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 02/14/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance.


The UCSD Department of Obstetrics, Gynecology, and Reproductive Sciences conducts clinical, translational, and basic research on a variety of developmental biology and reproductive and women’s health areas. The Laurent group utilizes transdisciplinary approaches to understand the mechanisms underlying pregnancy complications and to discover biomarkers that can be used to predict and diagnose them.

Applies advanced computational, computer science, data science, and CI software research and development principles, with relevant domain science knowledge where applicable, to perform highly complex research, technology and software development which involve in- depth evaluation of variable factors impacting medium to large projects of broad scope and complexities. Designs, develops, and optimizes components / tools for major HPC / data science / CI projects. Resolves complex research and technology development and integration issues. Gives technical presentations to associated research and technology groups and management. Evaluates new hardware and software technologies for advancing complex HPC, data science, CI projects. May represent the organization as part of a team at national and international meetings, conferences and committees. Assists in the design, implementation and recommends new hardware and software technologies for advancing complex HPC, data science, CI projects. Acts as a project manager and may lead a team of research and technical staff.

This position will focus on the analysis of whole genome, exome, transcriptome and epigenome datasets in the Laurent lab at UCSD. The incumbent will collaborate with investigators at UCSD and other institutions, including the San Diego Zoo Wildlife Alliance, by performing analysis of multi-omic data, including RNA-seq, ChIP-seq, ATAC-seq, and DNA methylation data. The incumbent is responsible for managing projects and performing analysis of next generation sequencing datasets, biological interpretation of analysis results, interfacing with faculty and investigators, performing outreach and educational activities, and developing and implementing data analysis methods using cloud computing and high performance computing.


  • Nine (9) years of related experience, education/training, OR an Bachelor’s degree in related area plus five (5) years of related experience/training.

  • Advanced knowledge of HPC / data science / CI.

  • Highly advanced skills, and demonstrated experience associated with one or more of the following: HPC hardware and software power and performance analysis and research, design, modification, implementation and deployment of HPC or data science or CI applications and tools of large-scale scope.

  • Demonstrated ability to initiate research proposals and acquire funding.

  • Proven ability to communicate technical information to technical and non-technical personnel at various levels in the organization and to external research and education audiences.

  • In depth skills and experience in independently resolving complex computing / data / CI problems using introductory and / or intermediate principles.

  • Advanced experience working in a complex computing / data / CI environment encompassing all or some of the following: HPC, data science infrastructure and tools / software, and diverse domain science application base.

  • In depth ability to successfully work and / or lead multiple concurrent projects. Demonstrated research and technology project leadership and management skills.

  • In depth experience assessing a broad spectrum of technical and research needs and demands and establish priorities, delegate and / or lead development of solutions to meet such needs.

  • Advanced experience in one or more of the following: optimizing, benchmarking, HPC performance and power modeling, analyzing hardware, software, and applications for HPC / data / CI.

  • Expert knowledge and research experience with NGS data analysis in the areas of genome analysis, transcriptomics and/or epigenomics.


  • Master's degree in Computer / Computational / Data Science, or Domain Sciences with computer / computational / data specialization preferred.
  • Ph.D. degree in Biology / Bioinformatics / Computer Science or related field preferred.


  • Employment is subject to a criminal background check.

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see:

UC San Diego is a smoke and tobacco free environment. Please visit for more information.

Application Instructions

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