Spatial and Functional Genomics Research Associate - 121680
#121680 Spatial and Functional Genomics Research AssociateExtended Deadline: Fri 6/2/2023
UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply.
For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy
UCSD Layoff from Career Appointment: Apply by 02/22/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 03/03/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance.
*Depending on the experience of the selected candidate, this position will be hired at the SRA 1 or SRA 2 NEX level.*
The mission of the UCSD Center for Epigenomics is to develop a quantitative and molecular framework to study the function and regulation of the human genome, with the ultimate goal to understand the molecular basis of cancer and other human diseases. Epigenomics is at the forefront of Precision Medicine.
The epigenome, a term referring to the state of DNA methylation and the covalent modifications of histone proteins in a cell, plays a central role in regulating the functional output of the genome during development. Changes in the epigenome that result from exposure to stress, pathogenic conditions and during aging can determine the patterns of gene expression and predispose an individual to diseases. Epigenome research promises to significantly improve our understanding of the factors that drive human development and disease. The UCSD Center for Epigenomics will work with researchers on the UCSD campus and beyond to foster the application of epigenomic concepts and technologies to clinical, translational, and basic research.
Under the direction of the Associate Director of Spatial and Functional Genomics, the Spatial and Functional Genomics Research Associate will perform molecular, cell biology, and biochemical experiments from biological samples including animal and human tissues. The Research Associate will be a hands-on experimentalist for the Center’s Spatial and Functional Genomics platform and will play a key role in setting up imaging-based single cell spatial genomics assays, viral vector-mediated high-throughput DNA cis-element reporter assays as well as CRISPR mediated gene expression perturbation screenings.
The incumbent will participate in experimental design and be responsible for careful record keeping, operating laboratory equipment, troubleshooting, quality control, and periodically summarizing results for supervisors. Additional duties include contributing to laboratory management, organization of laboratory reagents, and maintenance of laboratory equipment. Performs other duties as assigned.
Theoretical knowledge in molecular biology and biological research or related field as typically attained by a bachelor’s degree and/or an equivalent combination of education and experience.
Experience with performing molecular biology techniques such as RNA or DNA FISH, IF staining, PCR and quantitative PCR. Hands-on experience with assays such as RNA-seq is a plus, but not required.
Experience with the operation of a personal computer and software application, such as MS Word and Excel. Experience in a Linux command environment is a plus, but not required.
Proven ability to read, comprehend, and discuss research materials.
Excellent organizational skills and attention to detail.
Demonstrated ability to maintain effective working relationships in a diverse laboratory environment.
Proven ability to communicate effectively with other research staff, and function as a member of a research team. Ability to maintain effective working relationships in a diverse laboratory environment.
Enthusiasm for learning new techniques, and working in a fast-paced "startup" atmosphere.
Strong theoretical knowledge in molecular biology, cell biology and biochemistry, especially RNA biology, and biological research.
Demonstrated ability to perform molecular cloning and mammalian cell culture.
- Experience with operating advanced microscopy and next-generation-sequencing sample preparation.
- Help to design and maintain reporting infrastructure to meet the needs of supervisors, and collaborators. Prepare reports in accordance with supervisor/collaborator needs and requirements, following research center reporting standards.
- Job offer is contingent upon satisfactory clearance based on Background Check results.
- Occasional evenings and/or weekends may be required.
- Willingness to work with animals, lentivirus, radioactive material, human tissue and standard hazardous laboratory compounds.
Pay Transparency Act
Annual Full Pay Range: $51,949 - $61,972 (will be prorated if the appointment percentage is less than 100%)
Hourly Equivalent: $24.88 - $29.68
Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.
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UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html
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UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.
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Job Reference #: 121680