Staff Research Associate III - 116428
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#116428 Staff Research Associate IIIExtended Deadline: Wed 7/13/2022
For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy
UCSD Layoff from Career Appointment: Apply by 5/20/22 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 5/31/22. Eligible Special Selection clients should contact their Disability Counselor for assistance.
This position will remain open until filled.
The multi-disciplinary laboratory within the Department of Pediatrics works in the fields of RNA and Chemical biology. The laboratory explores the role of RNA modifications in cancer, immunity, and stem cell biology. Projects in the lab use cell culture, animal models, neural stem cells, 3D organoids, human pluripotent cells and several molecular tools to investigate fundamental mechanisms of cancer development, AIDS, COVID, and immune disorders.
Under general supervision of the Principal Investigator, the Staff Research Associate III will perform cellular and animal lab experiments, making significant independent contributions in the design, troubleshooting, modification and analysis of experiments and protocols. Incumbent will also perform experiments using tissue culture techniques such as PCR, plasmid purification, iPSC production and characterization, and HT screening and sequencing, gene silencing, cloning, CRISPR genome editing, cancer models, drug treatments, under general supervision. In addition, the incumbent will independently support duties to include RT-PCR, qPCR, DNA and RNA molecular experiments, western blotting, immunoprecipitation, affinity purification, analyze and report data, prepare complex solutions, reagents and culture media and run cell analyses to ensure quality and control.
The incumbent will be responsible for implementing and performing a variety of new and on-going experimental protocols, making significant research contributions to the laboratory and making innovative contributions pertaining to complex experimental procedures of iPSC production and characterization. May provide training and direction and work cooperatively with other SRAs, including doctoral and student lab assistants. Compile and analyze research data, draft articles and grant proposals.
Advanced theoretical knowledge of and direct experience with Stem Cell biology as typically attained by a Bachelor's degree or an equivalent combination of education and experience.
Strong experience with research design, protocol development, and qualitative and quantitative research methods to independently address scientific challenges to move the project forward.
Direct experience overseeing research projects.
Demonstrated experience authoring journal articles, abstracts, and posters. Ability to prepare papers for publication and research proposals. Ability to read, comprehend and discuss research materials. Review the scientific articles and make innovative contributions to develop new research techniques and improve current protocols for the research projects.
Proven knowledge of microscopy imaging procedures and in vivo analysis.
Strong experience in analysis and management of complex data.
Strong demonstrated experience in qualitative research methods.
Proficiency in the use of computer based spreadsheet, database, word processing communications and statistical applications (e.g., EXCEL, SPSS, ACCESS, WORD, ENDNOTE, POWER POINT, SAS).
Experience with RT-PCR, qPCR, DNA and RNA molecular experiments, western blotting, immunoprecipitation, affinity purification, analyze and report data, prepare complex solutions, reagents and culture media and run cell analyses.
Proven ability to perform scientific procedures including confocal microscopy, DNA and RNA isolation, and histological analysis.
Advanced knowledge and experience working with and handling small animals including mice. Knowledge of normal physiological data of rodents, particularly mice. Experience with small animal husbandry and excellent organizational skills to manage all lab animal work.
Knowledge of laboratory safety including radioactive/biohazard handling and disposal techniques, and the ability to ensure laboratory compliance with required safety regulations.
- Ph.D. in cell biology, biochemistry, chemical biology, or genetics.
- Employment is subject to a criminal background check.
- Occasional evenings and weekends may be required.
- Must be willing to work with hazardous materials.
- Must have access to reliable transportation.
- Must be willing to work with small animals.
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
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