Senior Research Technician - 120075
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#120075 Senior Research TechnicianInitial Review Date: Thu 11/17/2022
UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply.
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This is a UC San Diego Internal Recruitment open to UCSD and UCSD Health System Staff Only
UCSD Layoff from Career Appointment: Apply by 11/15/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 11/17/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The Division of Infectious Diseases in the Department of Medicine was established in 1969 and since then has grown to have 40+ faculty members. Our research space is located in several buildings on and off campus including the Clinical Teaching Facility, the Antiviral Research Center in Hillcrest, the Stein Clinical Research Building, the Moores Cancer Center, the Biomedical Research Facility, the San Diego VA Medical Center, the Cellular and Molecular Medicine East Building, and the George Palade Laboratories for Cellular and Molecular Medicine. Major international collaborations in Mozambique, Mexico, India, South Africa and Peru play important roles in the Division’s expansion of its international programs.
The division continues to grow and expand with the development of our international medicine program, as well the ongoing studies and interests of our faculty.
Under the general supervision of the Program Director, the incumbent directs and supports research studies for specific Principal Investigators at the Center for AIDS Research/HIV Institute at UCSD. The incumbent has advanced knowledge of HIV and other globally important infectious diseases and has experience in translational and basic virology research. Will contribute to multiple research studies, as needed, throughout the project cycle, from study design to final report, with particular emphasis on flow cytometry. Incumbent has experience in and is health cleared for work within a BSL3.
Incumbent regularly communicates with clinical and laboratory study team members to promptly identify challenges and to ensure that clinical research methods, laboratory procedures, data processing methods and statistical analyses remain aligned with study objectives. On multiple studies, assists in the establishment, review and troubleshooting of wet laboratory procedures, particularly methods for quantification of nucleic acids and proteins by digital PCR, real-time PCR, and ELISA. Design and review of high throughput methods for studying cytosine methylation in the HIV provirus from clinical samples is expected. Will be principally responsible for quantitative analysis of sample handling, storage and processing protocols to identify sources of error, to incorporate error estimates into analyses, and to troubleshoot new methods.
Incumbent contributes to the preparation and editing of grant review proposals for federal, state and private funding agencies. Will draft, edit or criticize proposal aims and research plans. Elements of proposed studies involving evaluate the epigenetic components of both latent HIV and SIV in understanding the epigenetics of HIV latency.
Will analyze, discuss and may record sensitive data, including personal health information, in compliance with established laboratory protocols, institutional requirements of the University of California, UC San Diego Health and the Veterans Administration Healthcare System, and applicable government regulations. Will train lab members and oversee team compliance with these requirements. Is accountable for performing all duties with scientific integrity and for safeguarding patient confidentiality and digital data security.
Advanced theoretical knowledge of infectious diseases, specifically, understanding of HIV infection, including dynamics in vivo, clinical sequelae and assays.
Demonstrated familiarity with epigenetic mechanisms that are responsible for in vivo HIV-1 latency.
Demonstrated familiarity with BSL-3 workspace and infectious agents.
Demonstrated experience in management of a staff involving complex projects or studies.
Demonstrated ability to obtain and respond to sensitive and personal health information in a professional manner.
Demonstrated organizational ability in handling multiple tasks with time sensitivity.
Demonstrated ability to work successfully both independently and in a team setting.
Excellent communication skills. Ability to facilitate in written and verbal communication with clinical researchers, laboratory technicians, statisticians, bioinformatics experts and administrative personnel.
Demonstrated experience with preparation of abstracts and manuscripts, and public-speaking in a wide variety of forums.
Proven ability to utilize a computer for tasks such as word processing and statistics. Specific knowledge of Word, Excel, Access, Power Point, SPSS, SAS, and Velos.
Demonstrated data processing experience including data entry procedures and quality assurance processes.
Familiarity with HIV research methods and ability to critically read published studies related to HIV translational research
Demonstrated ability to communicate effectively to participants and encourage continued involvement and participant retention. Demonstrated ability to work with diverse groups, employing cultural sensitivity and a high level of professionalism.
Thorough knowledge of applicable compliance requirements related to the use of human subjects in research.
Ability to identify trends in study participation and to develop strategies to maximize retention.
Demonstrated experience with statistical analysis of data in translational research studies.
Experience in blood processing and laboratory safety.
Proven experience in flow cytometry work and analysis.
Proven experience in successful preparation of research grant proposals for funding by NIH or other major funding source.
Experience with statistical analysis of digital PCR data, real-time PCR data or similar quantitative bio-assay data, especially experience with Bayesian statistical analysis involving missing or censored data.
Master’s degree or Doctoral degree in a related field.
Employment is subject to a criminal background check.
Scheduled work hours may vary to be early in the morning or later in the evening.
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
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