Research Associate - Neurosciences - 113982
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#113982 Research Associate - NeurosciencesExtended Deadline: Wed 6/1/2022
For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy
UCSD Layoff from Career Appointment: Apply by 01/14/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 01/25/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance.
Under supervision, this person will be responsible for carrying out experiments aimed at understanding the molecular mechanisms involved in neurodegeneration in Alzheimer's and Parkinson's diseases. The incumbent will perform tissue culture analysis, real time PCR, DNA methylation profiling, western blots, immunoprecipitation and cell assays. An important role in this position is maintaining the mouse colony, breeding, genotyping, performing minor surgeries, behavioral testing, drug administration and tissue collection. Basic managerial tasks will also be required, including general administration of the lab (arrange for equipment servicing; managing purchasing and documentation, maintaining updated records and compliance with EH&S and animal safety regulations.
Depending on the experience of the selected candidate, this position will be hired at the SRA 1 or SRA 2 level.
Theoretical knowledge in cell biology, biochemistry, molecular biology and genetics.
Expertise in molecular biology including RNA/DNA isolation, real-time PCR, viral production, plasmid cloning and preparation.
Demonstrated experience with tissue culture, preferably with neuronal cell lines.
Experience in basic biochemistry methods, including Western blot, primary neuronal cultures, ELISA assay, immunohistochemistry and basic microscopy.
Hands-on experience in rodent models of disease, including colony management (breeding; genotyping, weaning), basic surgical procedures, drug delivery (i.p. injections), tissue collection (brain).
Strong computer skills and experience with the operation of all basic software applications such as Word, PowerPoint and Excel, and knowledge to work with a variety of statistical and analysis programs like Prism, and learn specialized imaging and analysis software.
Excellent communication skills (both verbally and written) to interact professionally and effectively in a basic research environment, as well as accurately document research procedures. Ability to comprehend and discuss research materials.
Effective interpersonal skills including tact, diplomacy and flexibility. Ability to work independently and/or in a team framework in conjunction with principles of community and in a lab environment that interacts with a diverse group of people.
Knowledge of basic lab safety requirements, procedures, and EH&S regulations and methods for handling inventory, storing, clean-up, and waste disposal for biohazardous materials. Ability to maintain safe and orderly lab, maintain inventories, and order lab supplies.
- Knowledge of neurological disorders such as Alzheimer's Disease, Parkinson's Disease and related disorders.
- Experience with cutting-edge molecular biology techniques like RNA-seq; ChIP-seq; library preparation are highly preferred.
- Familiarity with behavioral testing on rodent models is a plus.
- Employment is subject to a criminal background check.
- Must be willing to work with hazardous materials.
- Must be available to work some weekends and evenings to complete experiments
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
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