Job Description

Payroll Title:
Hiring Pay Scale
$31.82 - $41.14 / Hour
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Variable, TBD

#130990 Research Associate III

Filing Deadline: Thu 7/25/2024

UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply.

UCSD Layoff from Career Appointment: Apply by 7/15/24 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 7/25/24. Eligible Special Selection clients should contact their Disability Counselor for assistance.


This is a part-time 50% Career position.

Under general supervision, the Staff Research Associate III will perform work that requires a combination of significant knowledge and skills in mouse developmental biology, islet biology, and diabetes modeling. Make significant innovative contributions pertaining to experimental design and methodology by reviewing published scientific data in referred journals, as well as online using search engines and subject-specific websites to make recommended changes and standards to current protocols and practices. Advise, consult, and collaborate independently with the principal investigator on experimental design, interpretation of results, research direction and new research projects.

The incumbent will perform a variety of different laboratory procedures encompassing standard and specialized laboratory procedures including: management of a large and complex transgenic mouse colony inventory, collection of mouse tissues, processing of tissue for immunohistochemical analysis, mouse surgical procedures, isolation of mouse islets, inducing and monitoring diabetes in mice, confocal microscopy imaging an analysis. Requires extensive working knowledge of molecular genetics, mouse husbandry, and molecular biology, as well as laboratory procedures, including regulatory compliance.

The incumbent will take a prominent role in the management of the laboratory. The position will also involve overseeing lab safety protocols and procedures and ensuring lab members are trained in all required lab safety practices. This will include maintaining a lab environment that is in compliance with all laboratory safety rules and regulation, coordinating with regulatory agencies to schedule and conduct routine safety audits, and keeping-up-to-date records of safety training documentation. Duties also include (1) implementing and modifying metabolic tests in mice to meet the needs of the research project, (2) training laboratory staff in mouse tissue isolation, including isolation of pancreatic islets, preparation of pancreatic tissue slices, transplantation procedures, and metabolic testing methods, (3) supervising, training, and directing laboratory staff on mouse colony management, mouse surgeries, and metabolic testing of mice, (4) managing laboratory assistants, (5) preparing and modifying protocols for all procedures, and (6) maintaining accurate records concerning methods for all procedures performed and all the results obtained. Under general direction of the P.I., the incumbent also prepares written reports describing the experimental procedures and findings.


  • Advanced theoretical knowledge in Biology or related field, as typically acquired by a Bachelors degree, or an equivalent combination of experience and education.

  • Proven experience in managing a mouse colony, including ear marking, tail clipping, and mouse breeding, and genotyping.

  • Proven experience in DNA preparation, PCR, gene cloning, restriction digestions, Southern blotting.

  • Extensive experience for preparing tissue for immunohistochemical studies, post fix, dehydrate, embed tissue blocks cryoprotected or in paraffin.

  • Demonstrated experience preparing tissue sections on cryostat and microtome.

  • Demonstrated experience with immunohistochemical techniques.

  • Extensive knowledge of mouse anatomy; proven experience in immunohistochemistry and in situ hybridization.

  • Demonstrated experience maintaining a database for mouse colony (File Maker Pro).

  • Excellent organizational skills to keep inventory, maintain equipment, etc.

  • Demonstrated skill and extensive experience with transplantation experiments in mice.

  • Experience with light and fluorescence microscopes and image acquisition.

  • Advanced knowledge, demonstrated skill and extensive experience with islet collection, preparation and analysis.

  • Demonstrated experience in interpreting, troubleshooting, and analyzing results of scientific experiments.

  • Working knowledge of various computer software, hardware, and standard office sufficient to record scientific data and results and prepare reports.

  • Effective and diplomatic oral and written communication and interpersonal skills. Ability to work with a variety of personnel including staff, researchers, and academic supervisors.

  • Proven knowledge of MSDSs (Material Data Safety Sheets) and the hazard communication and Injury and Illness and Prevention Program (IIPP). Knowledge of laboratory safety precautions including appropriate clothing, safe handling of chemicals, and the use of protective items.


  • Job offer is contingent upon satisfactory clearance based on Background Check results.

  • Must be willing to work evenings and weekends when necessary.

Pay Transparency Act

Annual Full Pay Range: $66,441 - $106,839 (will be prorated if the appointment percentage is less than 100%)

Hourly Equivalent: $31.82 - $51.17

Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).

If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements.

To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community.

UC San Diego is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

For the University of California’s Affirmative Action Policy please visit:
For the University of California’s Anti-Discrimination Policy, please visit:

UC San Diego is a smoke and tobacco free environment. Please visit for more information.

Application Instructions

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