Research Associate - 118183
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#118183 Research AssociateExtended Review Date: Wed 9/7/2022
For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy
This position will remain open until a successful candidate has been identified.
UCSD Layoff from Career Appointment: Apply by 08/11/22 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 08/22/22. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The Moores Cancer Center is one of just 51 in the United States to hold a National Cancer Institute (NCI) designation as a Comprehensive Cancer Center. As such, it ranks among the top centers in the nation conducting basic and clinical cancer research, providing advanced patient care and serving the community through outreach and education programs.
The Cancer Center's mission is to translate promising scientific discoveries into new and better options for the care of patients with cancer. The Center supports one of the broadest ranges of cancer activities in the nation - from fundamental and translational cancer research in molecular genetics and advanced molecular therapeutics, and from population studies of cancer incidence to community education about cancer prevention and risk reduction.
Under general supervision, working in an immunology research laboratory, the Research Associate will independently conduct experiments involving flow cytometric analysis of human and mouse leukemia cells. Primary responsibilities are preparing samples for staining with specific monoclonal antibodies for flow cytometry, and collecting, analyzing, organizing, and summarizing the results using Flowjo, Cellquest and Excel software. Additional responsibilities include assisting in the development, screening, characterization and validation of monoclonal antibodies generated against cancer cell targets. Will also oversee several areas of general laboratory maintenance to assure compliance with all safety and other regulatory training.
Theoretical knowledge of immunology, molecular biology, cell biology, and protein chemistry and/or related fields acquired through a Bachelor's degree and/or equivalent education and/or experience.
Knowledge of and experience with proteins, monoclonal antibody production, and biochemical procedures such as purifying and conjugating monoclonal antibodies.
Strong knowledge and experience in flow cytometry and operation of a FACSCalibur instrument. Design, perform, and interpret results from experiments with human and mouse cells stained with specific fluorochrome-conjugated monoclonal antibodies.
Experience with reading and reviewing protocols and new techniques, and using that information to design experiments with limited supervision.
Demonstrated experience analyzing and interpreting data.
Knowledge, experience and willingness to handle blood, plasma and other human specimens for processing and shipping. Be willing and able to work with human samples, animals, biohazardous materials and radioactivity.
Effective interpersonal, written and verbal communication skills (using grammatically correct written English and accurate typing) to interact with a variety of personalities at all levels of the organization, exercising tact, mature judgment, diplomacy, and flexibility to promote positive working relationships and job effectiveness. Excellent phone etiquette skills.
Experience and familiarity with the operation and maintenance of basic laboratory equipment, such as centrifuges, spectrophotometers, balances, pH meters, autoclaves and electrophoresis equipment.
Demonstrated knowledge and ability to use computer software applications including word processing and database applications (FlowJo, Cellquest, Filemaker Pro software) and email. Accurate computer word-processing and database skills.
Knowledge and understanding of primary and cell lines and excellent tissue culture technique.
- Ability to perform standard molecular biology techniques, including PCR, SDS Page electrophoresis, western blotting, ELISA assays, and recombinant DNA manipulation.
Employment is subject to a criminal background check.
Must be able to maintain confidentiality.
Must be willing and able to work weekends and evenings when necessary.
Must be able to handle blood samples and be trained for biohazards.
Must be willing to handle biohazard and radioactive materials and animals.
Must successfully complete annual TB screen.
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
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