Laboratory Research Associate - 125324
Job Description
#125324 Laboratory Research Associate
Filing Deadline: Mon 10/2/2023UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply.
For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy
UCSD Layoff from Career Appointment: Apply by 09/21/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 10/02/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance.
DESCRIPTION
The Moores Cancer Center (MCC) is one of just 53 NCI-designated Comprehensive Cancer Centers in the United States and the only one in San Diego County. As a consortium cancer center, it is a collaborative partnership between the UCSD: encompassing 28 departments, 6 schools (School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, School of Public Health, Jacobs School of Engineering, School of Biological Sciences & the School of Physical Sciences), UCSD Health oncology hospitals and clinics; the basic and public health research and outreach of San Diego State University (SDSU), and the basic and translational research of the La Jolla Institute of Immunology (LJI). These various programs and units are all dedicated to fulfilling the Moores Cancer Center's mission of reducing cancer's burden. As such, it ranks among the top centers in the nation conducting the continuum of cancer research, providing advanced patient care, and serving the community through outreach and education programs. As a top-ranking, future-oriented organization, we offer challenging career opportunities in a fast-paced and innovative environment. Moores Cancer Center follows a progressive philosophy of career-path development for its employees including opportunities for cross-training, professional development, and progressive responsibility.
MCC's mission is to transform cancer care in our catchment area and beyond by driving exceptional scientific discoveries and innovations in prevention, detection, care, and training. MCC will make a global impact on improving health by reducing cancer burden through accelerated discovery and translation, compassionate and interdisciplinary care, education and community engagement, with the foundation of our core values - Excellence, Innovation and Risk-Taking, Collaboration, Diversity and Service.
The Laboratory Research Associate will be expected to contribute to the independent design, conduct, and analysis of experiments and their results and also preparation, presentation, and publication of results under the general direction of the Principal Investigator (PI). Make significant innovative contributions pertaining to the design and overall direction of scientific research projects and propose possible changes or new directions in the course of the investigations. Read and evaluate scientific articles relevant to current research studies, finding new sources of information. The incumbent will be responsible for applying or adapting scientific techniques and assisting with the planning and scheduling of research procedures, recording the results of studies, compiling and analyzing data including statistical analyses, and preparing charts and graphs. Scientific intellect especially as it pertains to the immunology and molecular biology is essential. The incumbent will independently maintain and manage an animal breeding colony consisting of approximately 150 cages of animals, maintain laboratory equipment, order supplies as needed and assist laboratory management to provide support for students, postdocs and general laboratory operations.
Multiple myeloma, a tumor of plasma cells, ranks as the second most common type of blood cancer. Our laboratory is very active in the development of novel myeloma animal models to test novel targeted therapies and immunotherapies. We are also studying human primary cells obtained from myeloma patients, and our passion is to understand antigen-presenting cells (dendritic cells) and other myeloid regulatory cells operating at the myeloma tumor site.
MINIMUM QUALIFICATIONS
Advanced theoretical knowledge and/or Bachelor's Degree in immunology, molecular biology, and/or related work experience.
Demonstrated strong experience handling and working with small animals, including demonstrated experience conducting mouse surgeries, experiments, and injections. Knowledge in conducting euthanization of small animals.
Demonstrated strong experience performing DNA cloning and manipulation, lentiviral preps and transduction.
Demonstrated strong experience with protein biochemistry techniques; including quantification, ELISA assays, SDS PAGE, Western and Immunoblotting, phosphorylations and gel electrophoresis.
Demonstrated strong experience performing multi-parametric flow cytometry and cell sorting.
Demonstrated strong experience in cellular immunology techniques, such as cytotoxicity assays, ELISPOT, cytokine detection.
Demonstrated strong experience and knowledge in coordinating major mouse experiments, such as planning injection and drug treatment dosing schedule.
Demonstrated strong experience using laboratory equipment such as centrifuges, spectrophotometers, balances, pH meters, autoclaves and electrophoresis equipment.
Demonstrated experience performing sterile eukaryotic cell culture techniques, PCR and agarose gel electrophoresis.
Demonstrated experience using histological and immunohistochemical techniques to evaluate protein localization in fixed cells or tissues.
Demonstrated experience performing light, fluorescence and confocal microscopy techniques to visualize protein expression in tissue sections.
Demonstrated ability to follow verbal and/or written instructions, including follow-up on previously begun procedures. Demonstrated accurate record data and enter into appropriate medium. Detail-oriented.
Demonstrated experience in proper handling of chemical and biohazard materials. Demonstrated experience with sterile techniques.
Demonstrated experience to adhere to established UCSD guidelines for safety and environmental issues.
Experience with computer software such as Excel and Prism to analyze data, store results and compute raw data. Demonstrated experience of computer applications such as Word, Excel and PowerPoint. Internet search and software analysis capabilities.
Strong communication skills (both verbal and written) needed to interact professionally and effectively in the work environment, as well as to effectively and accurately document research procedures. Demonstrated ability to read, comprehend and discuss research materials.
Experience ordering and maintaining lab equipment and supplies.
Experience in troubleshooting problems for quality control on every immunochemical and histochemical procedures.
Experience and background in mouse/ human and cellular immunology.
PREFERRED QUALIFICATIONS
CRISPR/Cas9 experience.
CyTOF mass cytometry experience.
SPECIAL CONDITIONS
Employment is subject to a criminal background check and pre-employment physical.
Must be willing and able to work with hazardous materials (biological and chemical).
Must be willing and able to work with small animals.
Pay Transparency Act
Annual Full Pay Range: $64,506 - $103,727 (will be prorated if the appointment percentage is less than 100%)
Hourly Equivalent: $30.89 - $49.68
Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.
To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community.
UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html
UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.
UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.
Application Instructions
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