Lab Research Associate - 121783
#121783 Lab Research AssociateExtended Deadline: Mon 4/3/2023
UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply.
For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy
This position will remain open until a successful candidate has been identified.
UCSD Layoff from Career Appointment: Apply by 03/02/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 03/13/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The Moores Cancer Center is one of just 53 NCI-designated Comprehensive Cancer Centers in the United States and the only one in San Diego County. As a consortium cancer center, it is a collaborative partnership between the UCSD: encompassing 14 departments (12 clinical, 2 basic sciences), 3 professional schools (School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, School of Public Health), UCSD Health oncology hospitals and clinics; the basic and public health research and outreach of San Diego State University, and the basic and translational research of the La Jolla Institute of Immunology.
These various programs and units are all dedicated to fulfilling the Moores Cancer Center's mission of reducing cancer's burden. As such, it ranks among the top centers in the nation conducting the continuum of cancer research, providing advanced patient care, and serving the community through outreach and education programs. As a top-ranking, future-oriented organization, we offer challenging career opportunities in a fast-paced and innovative environment. Moores Cancer Center follows a progressive philosophy of career-path development for its employees including opportunities for cross-training, professional development, and progressive responsibility.
MCC's mission is to transform cancer care in our catchment area and beyond by driving exceptional scientific discoveries, and innovations in prevention, detection, care, and training. MCC will make a global impact on improving health by reducing cancer burden through accelerated discovery and translation, compassionate and interdisciplinary care, education and community engagement, with the foundation of our core values - Excellence, Innovation and Risk-Taking, Collaboration, Diversity and Service.
Under supervision, the Research Associate will perform experiments related to various cancer pharmacology and drug development research projects. 1) Maintain bacterial and tissue culture cell lines, and use them for production of novel proteins. 2) Conduct purification and characterization of recombinant proteins. 3) Test the activity of new cancer drugs in vitro and in in vivo in murine tumor models. 4) Design and construction of expression vectors. 5) Investigate the mechanism of action of novel cancer drugs and the changes underlying development of resistance. Additional functions include conducting biochemical, cell biological, fluorescent microscopic and molecular pharmacology experiments; maintaining laboratory equipment and providing support for general laboratory operations. Other duties assigned as needed.
Theoretical knowledge of biochemical, cell biology and molecular biology or a Bachelor’s of Science degree in a related field of science or equivalent in education and experience.
Experience working with small animals. Experience to obtain blood and perform mouse experiments and injections.
Experience performing molecular biology techniques including DNA and RNA isolation, PCR, RT-PCR, plasmid preparation and cloning.
Experience with the design and execution of complex flow cytometric analyses of cell lines and primary tissues.
Experience with the operation of HPLC instruments, the design of buffer and gradient systems and advanced understanding of chromatographic resins.
Experience with bacterial and advanced tissue culture techniques and maintenance of sterility.
Familiarity and experience with chemistry techniques including calculation of drug concentrations and preparation of complex buffers.
Ability to use expression vectors to produce recombinant proteins in mammalian, bacterial and insert cells.
Experience with the use of fluorochromes in biologic systems including the labeling of recombinant proteins and nucleic acids.
Familiarity with basic laboratory equipment such as centrifuges, spectrophotometers, balances, pH meters, autoclaves and electrophoresis equipment.
Experience with computer applications such as Word, Excel, PowerPoint and Prism. Advanced experience with internet search tools including PubMed.
Familiarity with proper handling of chemical and biohazardous materials. Ability to follow UCSD Safety and Hazardous Materials guidelines. Ability and willingness to work with hazardous materials. Understanding of safety procedures and guidelines.
Excellent communication skills both verbal and written. Ability to work professionally and harmoniously with others in an integrated project. Skill at prioritizing work to meet all deadlines and accurately document research procedures.
Ability to follow standard and advanced research protocols and to assist with solving research and methodological problems. Willingness and ability to learn new skills, research methods, and scientific principles. Absolute honesty regarding conduct of experiments and data.
Ability to read, comprehend and discuss research materials and published literature and prepare accurate and complete research reports.
- Employment is subject to a criminal background check.
- Must be willing and able to work with hazardous materials (biological and chemical).
- Must be willing and able to work with small animals.
- Must be available to work some weekend hours if needed.
Pay Transparency Act
Annual Full Pay Range: $56,564 - $90,995 (will be prorated if the appointment percentage is less than 100%)
Hourly Equivalent: $27.09 - $43.58
Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable).
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.
UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!
Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.
To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community.
UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html
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UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.
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Job Reference #: 121783