112370 - Genetic Research Associate
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#112370 Genetic Research AssociateFiling Deadline: Wed 10/27/2021
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UCSD Layoff from Career Appointment: Apply by 10/18/2021 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 10/27/2021. Eligible Special Selection clients should contact their Disability Counselor for assistance.
UCSD Department of Psychiatry is one of the most innovative and productive academic departments in the country, offering challenging career opportunities in the diverse areas of advanced educational programs, cutting-edge research, and state-of-the-art clinical services. The department is committed to offering a dynamic learning environment and growing opportunities to its talented and dedicated employees.
Under supervision of the Principal Investigator (PI) and senior laboratory members, the Research Associate will independently work on human genetic research projects aimed at identification of genes responsible for psychiatric disorders such as autism and schizophrenia. The incumbent will independently perform routine molecular biology techniques such as, but not limited to: PCR, DNA/RNA isolation, quantitative PCR, protein isolation, western blot techniques and genotyping. Independently perform PCR analysis of SNPS for mapping and gene identification. Perform RNA isolation and Northern blotting of candidate genes. Conduct protein extraction and Western Blotting of candidate genes. Other duties include mouse handling, tissue culture and CRISPR genome editing. Incumbent will assist with general laboratory maintenance including maintenance of tissue and DNA samples. Must work both independently and as part of a team, establishing and maintaining good working relationships with PI, post-doctoral fellows, and other members of the research group.
Theoretical knowledge of Biological Science, Biochemistry or Molecular Biology as typically attained by a Bachelor’s degree and/or an equivalent combination of education and experience.
Demonstrated knowledge of Molecular Biology techniques. Proven knowledge of experimental work or general laboratory experience.
General experience with a variety of laboratory equipment, including but not limited to PCR & RT-PCR machines, luminometers, incubators, centrifuges, autoclaves, spectrophotometers, & other molecular biology equipment.
Demonstrated knowledge of basic genetics and animal breeding.
Strong verbal and written communication skills to be effective in communicating and interacting with a diverse group of people within a research setting.
Ability to maintain accurate experimental records that allow subsequent replication, validation, or troubleshooting.
Theoretical understanding of basic statistical tests.
Excellent time management and strong demonstrated organizational and multi-tasking skills. Ability to establish priorities, meet multiple and frequently changing deadlines with flexibility. Detail oriented.
Experience with database and reporting tools such as Microsoft Word, Excel, Access, PowerPoint, Illustrator, Photoshop, Adobe, NCBI, UCSC Genome Browser.
General experience in performing standard and routine molecular biology techniques such as, but not limited to: PCR, DNA/RNA isolation, quantitative PCR, protein isolation, western blot techniques and genotyping.
General experience operating and maintaining a variety of laboratory equipment & tools, including but not limited to PCR & RT-PCR machines, luminometers, incubators, centrifuges, autoclaves, spectrophotometers, & other molecular biology equipment & tools.
Proven ability to handle, process, and store tissue, DNA, and other experimental samples; preparation of laboratory reagents and chemicals.
Willingness and ability to work with animals, mice as laboratory model system.
Ability to work carefully with potentially harmful agents and biohazardous materials.
Experience with immunohistochemistry and/or confocal microscopy.
Demonstrated experience with mouse colony maintenance, analyzing neurological phenotypes and genotype analysis.
Primary and immortal cell culture experience
Independent experience keeping a lab and experiment notebook.
Experience with preparing stock solutions and reagents, molar concentrations, autoclaving, bio- and chemical-hazards use and disposal, and sterile techniques
Proven ability to perform RNA isolation and Northern blotting of candidate genes.
Demonstrated experience conducting protein extraction and Western Blotting of candidate genes.
Employment is subject to a criminal background check.
Must be willing to work on evening and weekends if procedures require it.
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!
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