111609 - Staff Research Associate I
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#111609 Staff Research Associate IFiling Deadline: Tue 9/28/2021
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Special Selection Applicants: Apply by 9/28/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The Department of Pediatrics is one of the largest departments within the School of Medicine with approximately 171 Faculty, 50 post-doctoral fellows (both MDs and PhDs) along with over 300 support staff (not including hospital staff). In addition, the Department has 57 clinical residents and fellows distributed across the Divisions. The missions of research, education and patient care are intertwined, and are integral to the goals of the department.
The Department has undergone significant growth in recent years with a consolidated budget of approximately $106 million including sponsored projects expenditures of approximately $54 million and clinical revenue of over $ 52 million. This expansion of the Department’s research and clinical portfolio is expected to continue in the next few years.
The Department’s 18 divisions include Academic General Pediatrics, Child Development & Community Health; Allergy, Immunology and Rheumatology; Cardiology; Dermatology; Dysmorphology; Emergency Medicine; Endocrinology; Gastroenterology; Genetics; Genome Information Sciences; Hospital Medicine; Infectious Diseases; Neonatology; Nephrology; Pharmacology & Drug Discovery; Rehabilitation Medicine; and Respiratory Medicine.
In 2001, physicians and leadership of the University of California, San Diego (UCSD), Rady Children's, and Children's Specialists of San Diego (CSSD) unified pediatric patient care, research, education and community service programs, creating a university-affiliated children's health system to serve the region. Over the past two decades, an extensive list of joint programs has developed, with many physicians and researchers playing a role at both institutions.
This affiliation has consolidated the clinical, teaching, research and public service programs of the UCSD School of Medicine's Department of Pediatrics with San Diego's only health care system dedicated to the health and well-being of children. In 2009, this partnership was furthered by the creation of Rady Children’s Specialists of San Diego, a Medical Foundation, and is now recognized as having global leaders in research, technology, translational medicine, education and clinical excellence.
The Knight lab has for the last few years consisted of a team of approximately 35 highly skilled researchers, students and technicians, with an annual operating budget of about $3 million derived from a mixture of federal and non-federal sources. Most of the lab’s work focuses on technologies for reading out microbial communities, including laboratory procedures for next-generation sequencing and bioinformatics software development, with applications in the human microbiome and child development, conservation, environmental monitoring and management, and biofuels. The Knight lab is widely regarded as a leader in the microbiome field, publishing regularly in top journals including Science, Nature, Cell, and PNAS, and publishing several dozen journal articles per year overall.
With the move from CU Boulder to UCSD, these operations will scale up considerably, requiring new laboratory and computational infrastructure, software development (especially capacity for handling patient data and managing collaborations with companies that include confidential data), and multi-omics readout techniques. We are also currently in the planning phase for developing a broader microbiome center, which would act as a core facility for microbiome readout for a wide range of projects at UCSD and beyond.
Under general supervision of the Laboratory Manager, the SRA 1 assists with extracting, purifying, and analyzing DNA and RNA for Next Gen Sequencing and rapid response sequencing. Assists with new technology development in support of the research program, including documenting the feasibility of new technologies and testing of new technologies. Assists in maintaining new equipment and technologies including Next Gen sequencing equipment.
Theoretical knowledge of basic human genetics and molecular biology.
Experience with biology techniques such as PCR, gel electrophoresis, sequence analysis, RT-PCR, DNA/RNA isolation.
Demonstrated ability to follow university Environmental Health and Safety requirements. Experienced in working and maintaining a sterile environment.
Micropipetting and dilutions experience.
Knowledge and experience in liquid handling automation and ability to use validated protocols.
Knowledge of next generation sequencing for high throughput pipeline. Ability to perform validated protocols.
Ability to implement and troubleshoot protocols developed for high throughput sequencing pipeline.
- Experience writing/editing protocols and manuscripts.
- Computers skills using a Macintosh.
- Demonstrated experience with database management of clones/samples, including data entry, manipulation and creation of data reports.
Employment is subject to a criminal background check.
Incumbent must be available to work 9AM - 7PM, Monday-Friday and on occasional weekends.
Willing to work in a laboratory that collects, processes, stores, and assays biohazardous body fluids.
Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!
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