Job Description

Payroll Title:
Salary Range
Commensurate with Experience
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Monday-Friday

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.

#111419 Research Associate - Neurosciences

Filing Deadline: Mon 10/11/2021

For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus before they will be allowed on campus or in a facility or office. For more information visit:

UCSD Layoff from Career Appointment: Apply by 08/30/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 09/08/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.


Under supervision, this person will be responsible for carrying out experiments aimed at understanding the molecular mechanisms involved in neurodegeneration in Alzheimer's and Parkinson's diseases. The incumbent will perform tissue culture analysis, real time PCR, DNA methylation profiling, western blots, immunoprecipitation and cell assays. An important role in this position is maintaining the mouse colony, breeding, genotyping, performing minor surgeries, behavioral testing, drug administration and tissue collection. Basic managerial tasks will also be required, including general administration of the lab (arrange for equipment servicing; managing purchasing and documentation, maintaining updated records and compliance with EH&S and animal safety regulations.

Depending on the experience of the selected candidate, this position will be hired at the SRA 1 or SRA 2 level.


  • Theoretical knowledge in cell biology, biochemistry, molecular biology and genetics.

  • Expertise in molecular biology including RNA/DNA isolation, real-time PCR, viral production, plasmid cloning and preparation.

  • Demonstrated experience with tissue culture, preferably with neuronal cell lines.

  • Experience in basic biochemistry methods, including Western blot, primary neuronal cultures, ELISA assay, immunohistochemistry and basic microscopy.

  • Hands-on experience in rodent models of disease, including colony management (breeding; genotyping, weaning), basic surgical procedures, drug delivery (i.p. injections), tissue collection (brain).

  • Strong computer skills and experience with the operation of all basic software applications such as Word, PowerPoint and Excel, and knowledge to work with a variety of statistical and analysis programs like Prism, and learn specialized imaging and analysis software.

  • Excellent communication skills (both verbally and written) to interact professionally and effectively in a basic research environment, as well as accurately document research procedures. Ability to comprehend and discuss research materials.

  • Effective interpersonal skills including tact, diplomacy and flexibility. Ability to work independently and/or in a team framework in conjunction with principles of community and in a lab environment that interacts with a diverse group of people.

  • Knowledge of basic lab safety requirements, procedures, and EH&S regulations and methods for handling inventory, storing, clean-up, and waste disposal for biohazardous materials. Ability to maintain safe and orderly lab, maintain inventories, and order lab supplies.


  • Knowledge of neurological disorders such as Alzheimer's Disease, Parkinson's Disease and related disorders.
  • Experience with cutting-edge molecular biology techniques like RNA-seq; ChIP-seq; library preparation are highly preferred.
  • Familiarity with behavioral testing on rodent models is a plus.


  • Employment is subject to a criminal background check.
  • Must be willing to work with hazardous materials.
  • Must be available to work some weekends and evenings to complete experiments

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see:

UC San Diego is a smoke and tobacco free environment. Please visit for more information.

Application Instructions

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