Job Description

Payroll Title:
Salary Range
Commensurate with Experience
Moores Cancer Center
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Monday - Friday

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.

#110213 Senior Research Associate

Extended Deadline: Tue 9/28/2021

For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus before they will be allowed on campus or in a facility or office. For more information visit:

This position will remain open until a successful candidate has been identified.

UCSD Layoff from Career Appointment: Apply by 07/12/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 07/21/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.


The UCSD Department of Cellular and Molecular Medicine (CMM) is one of two basic science units in the School of Medicine where world-class researchers study fundamental cellular processes and pathways using a variety of techniques from classical genetics and fluorescence microscopy to high-throughput genomics, systems biology, and crystallography. Our 36 faculty and over 200 postdoctoral scholars, graduate students, and research staff work on the cutting edge of biology, cutting across fields from basic biochemistry and genetics to genomics, systems biology and stem cell biology. The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines and provide diversity to meet the interests of a broad spectrum of students and scholars. We constantly seek to recruit highly motivated, technologically-advanced, and deeply interested individuals who are ready to become a part of our dynamic research and educational environment.

Under general supervision, the incumbent will perform work that requires a combination of significant knowledge and skills in multiple scientific disciplines related to next generation sequencing technologies, environmental mutagenesis, molecular biology, and computational biology. The research associate will undertake research projects in collaboration with the Principal Investigator making significant innovative contributions pertaining to research projects funded by multiple private foundations and several federal research agencies. The overall operational goals of the lab are to generate novel genomics datasets using next-generation of sequencing approaches and to analyze these data with state-of-the-art machine learning approaches. These activities will require extensive background in cellular and molecular biology as well as some working knowledge in computational biology. The incumbent will take a prominent role in the overall management of the laboratory and will also perform mammalian cell culture experiments as necessary for the projects. Research responsibilities include independently designing, performing and interpreting results in the lab's research projects. Experiments may include small animal research.

The incumbent manages and organizes a 15-20 person research laboratory, ensuring that key operational procedures are in place to allow the lab's research to be performed optimally and efficiently; Orients and trains new lab personnel, ensuring they are compliant in all aspects of laboratory safety, that all relevant training is completed and that they are educated on equipment use; Trains new lab personnel on a number of Cell Culture, Molecular Biology, Biochemistry techniques; Provides work direction and oversight to the undergraduate lab assistants; Serves as Lab Safety Officer and carefully maintains training and laboratory records; Maintains lab supply inventories and submits, tracks and follows-up on lab purchases; and updates/submits rewrites/renewals of various laboratory protocols such as the Animal Use Protocol, Human Subjects Protocols, Biohazard Use Authorizations, Material Transfer Agreement, Data Use Agreement, and others. The incumbent will also monitor the workflow of different projects and, when appropriately, they will co-author research findings in prominent scientific journals and present findings at scientific meetings.


  • Strong theoretical knowledge in cellular and molecular biology, immunology, cancer biology, or related field typically acquired through formal education at the collegiate level and/or comparable experience.

  • Proven experience performing molecular biology techniques including PCR, DNA preparation/extraction, gel electrophoresis and Southern Blot.

  • Proven experience in performing biochemistry and laboratory techniques and demonstrated experience to prepare buffers and solutions, as well as various staining solutions.

  • Demonstrated experience in following step wise experimental protocols.

  • Proven ability to apply and use scientific knowledge to analyze and optimize experimental protocols.

  • Experience with general lab maintenance including cleaning, stocking supplies.Demonstrated ability to follow established Safety and Biohazardous Material Guidelines.

  • Knowledge of basic laboratory safety, rules and regulations. Knowledge of UC San Diego EH&S guidelines, etc. preferred.

  • Proven ability to effectively train fellow lab members in specialized molecular biology and biochemical techniques. Ability to read, comprehend and discuss research materials.

  • Ability to maintain effective working relationships with other staff members, students, faculty and scientists in a multi-cultural lab.

  • Strong ability to maintain effective organization of very large amounts of experimental data and metadata.

  • Willing to comply to UCSD policies and procedures and to stay informed and comply with basic safety rules and issues.

  • Experience with the operation of a personal computer and software application, such as Access, MS Word and Excel.

  • Experience contributing to the design, performance, troubleshooting, modification and analysis of experiments and protocols.


  • Knowledge of UCSD purchasing processes and procedures.


  • Employment is subject to a criminal background check.
  • Occasional evenings and weekends may be required.
  • Must be willing to work with carcinogens, mutagens, infectious agents and animals.

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see:

UC San Diego is a smoke and tobacco free environment. Please visit for more information.

Application Instructions

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