Job Description

Payroll Title:
CANCER CENTER/Solid Tumor Therapeutics
Salary Range
Commensurate with Experience
Moores Cancer Center
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Monday - Friday

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.

#110044 Research Associate

Extended Review Date: Wed 9/22/2021

For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus before they will be allowed on campus or in a facility or office. For more information visit:

This position will remain open until a successful candidate has been identified.

UCSD Layoff from Career Appointment: Apply by 07/13/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 07/22/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.

This position will be hired at the Staff Research Associate 1 or Staff Research Associate 2 level depending on the experience of the selected candidate.

Please Note: Changes have been made to the description and qualifications for this position on 9/15/21.


The Moores Cancer Center is one of just 50 in the United States to hold a National Cancer Institute (NCI) designation as a Comprehensive Cancer Center. As such, it ranks among the top centers in the nation conducting basic and clinical cancer research, providing advanced patient care and serving the community through outreach and education programs.

The Cancer Center's mission is to translate promising scientific discoveries into new and better options for the care of patients with cancer. The Center supports one of the broadest ranges of cancer activities in the nation - from fundamental and translational cancer research in molecular genetics and advanced molecular therapeutics, and from population studies of cancer incidence to community education about cancer prevention and risk reduction.

Under supervision, assist with gastrointestinal stromal tumor (GIST) cell culture such as cell propagation, mycoplasma testing, cryopreservation, and compound treatment. Assist with protein lysate preparation and quantification, SDS PAGE, as well as immunoblotting. Assist with mouse genotyping using established PCR protocols. Work with mice and assist with procedures such as surgery, euthanization, injections, tissue and/or tumor harvesting, and therapeutic treatment. Assist with immunohistochemistry of frozen and fixed samples. Maintain lab organization, receive lab ordered supplies, and prepare common buffers/reagents/solutions for experiments. Assist in the preparation of data for publication.


  • Theoretical knowledge of molecular biology, cell biology, genetics, and/or biochemistry.

  • Familiarity with molecular biology techniques including PCR, RT-PCR, RNA/DNA isolation, and protein purification. Ability to perform SDS-PAGE.

  • Ability to perform aseptic cell/tissue culture techniques. Familiarity with cell culture techniques such as cell propagation, mycoplasma, contamination testing, and cryopreservation.

  • Ability to assist with immunohistochemistry of frozen and fixed samples.

  • Ability and willingness to handle and work with small animals. Experience to assist with mouse genotyping. Ability to assist in performing mouse surgeries, experiments, injections, euthanasia and tissue recovery. Experience with murine gastrointestinal models.

  • Familiarity with basic laboratory equipment such as centrifuges, spectrophotometers, balances, pH meters, autoclaves and electrophoresis equipment.

  • Basic understanding of computer applications such as Word, Excel and PowerPoint.

  • Strong communication skills (both verbal and written) needed to interact professionally and effectively in the work environment, as well as to effectively and accurately document research procedures. Ability to read, comprehend and discuss research materials.

  • Ability to maintain confidentiality. Organizational skills to order and maintain lab equipment and supplies.

  • Detail-oriented. Ability to work with little supervision. Ability to follow verbal and/or written instructions. Ability to follow-up on previously begun procedures. Ability to accurately record data and enter into appropriate medium.

  • Good organizational skills and ability to prioritize work.

  • Enthusiasm for learning and a genuine interest in scientific research. Willingness and ability to learn new skills, research methods, and scientific principles.

  • Ability to adhere to established UCSD guidelines for safety and environmental issues.

  • Familiar in proper handling of chemical and biohazard materials. Familiarity with sterile techniques.

  • Theoretical and practical knowledge of cellular and molecular biology; their techniques and approaches, with demonstrated ability to perform independent scientific inquiry or equivalent experience.


  • Experience with immunoblotting for ER stress pathways.

  • Experience with gastrointestinal stromal tumor cells.

  • Internet search and software analysis capabilities. Knowledge and experience with GraphPad Prism.


  • Employment is subject to a criminal background check.

  • Must be willing and able to work with small animals.

  • Must be willing and able to work with hazardous materials (biological and chemical).

  • Must be able to occasionally work on evenings and weekends.

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see:

UC San Diego is a smoke and tobacco free environment. Please visit for more information.

Application Instructions

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