Job Description

Payroll Title:
Salary Range
Commensurate with Experience
Moores Cancer Center
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Monday - Friday

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.

#108598 Senior Laboratory Scientist

Extended Deadline: Mon 9/27/2021

For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus before they will be allowed on campus or in a facility or office. For more information visit:

This position will remain open until a successful candidate has been identified.

UCSD Layoff from Career Appointment: Apply by 04/20/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 04/29/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.


The Moores Cancer Center is one of just 51 in the United States to hold a National Cancer Institute (NCI) designation as a Comprehensive Cancer Center. As such, it ranks among the top centers in the nation conducting basic and clinical cancer research, providing advanced patient care and serving the community through outreach and education programs.The Cancer Center's mission is to translate promising scientific discoveries into new and better options for the care of patients with cancer. The Center supports one of the broadest ranges of cancer activities in the nation - from fundamental and translational cancer research in molecular genetics and advanced molecular therapeutics, and from population studies of cancer incidence to community education about cancer prevention and risk reduction.

Independently design and execute complex in vivo animal studies in mouse models of solid tumors in order to meet existing grant objectives/milestones and other cooperate funding objectives that support translational cancer research, including immunotherapy and other therapy. Manage and coordinate research efforts with other collaborators as appropriate for multidisciplinary research. Plan, execute and follow-up on high level regular and ad hoc meetings of investigators and management. Independently conceive, plan, and conduct research projects based on reviews of scientific literature and recent advances in related fields, organizing and executing all techniques involved. Contribute novel ideas of major methodological significance to the research projects, designing key experiments and developing new techniques. Author or co-author scientific journal manuscripts and book chapters. Report directly to funding agencies and journal editors. Prepare and implement research study budgets based on analysis of data. Direct and advise the work of technicians, students, and post-doctoral fellows to enable them to successfully participate in laboratory projects. Perform other duties as needed.


  • Extensive theoretical knowledge of virology, biochemistry, cellular and molecular biology and/or Bachelor's Degree, including experience in establishing, maintaining, and transfecting virus and/or equivalent education/experience.

  • Experience in designing, coordinating, executing, and analyzing data from in vivo studies using fluorescent mouse models of cancer/oncology.

  • Experience performing intramural and subcutaneous injections, dissection of animal pathological analysis, and in vivo quantitative imaging.

  • Demonstrated experience in cancer/oncolytic rodent models to determine cell burden/fate.

  • Skill in experimental design and adaptation of methods to achieve results. Experience in integrating data from multiple sources to synthesize conclusions. Knowledge and ability to read and abstract scientific articles and apply to the design of experiments.

  • Experience in the official review of manuscripts for publication in peer-review journals, and in the evaluation of grant proposals for potential funding.

  • Experience in providing technical work direction and training of students, post-docs, and technicians.

  • Experience in procuring funding by designing and executing experiments, analyzing data and deriving conclusions, developing experimental plans based on results from those preliminary studies, and writing all components of grant applications. These components include Abstracts, Specific Aims, Background and Significance, Preliminary Studies, Research Design and Methods, Budgets, Personnel, Animal Protocols, and revisions of applications based on Reviewer’s comments.

  • Experience and knowledge in developing hypotheses, design experiments, conduct experiments, analyze data, write manuscripts, and publish results in peer-reviewed journals, including all interactions with Reviewers and Editors.

  • Experience in managing multi-center projects and working under milestones driven projects, including knowledge in writing reports and experience in communicating with extramural funding.

  • Experience in designing and performing next generation RNA sequencing samples preparation and analyses.

  • Demonstrated experience in DNA and RNA extraction and use of extracted products in various PCR methods.

  • Expertise in building and managing biobanking of primary patient samples, including generating web page tracking sites for sample shipment and follow-up.

  • Strong organizational skills, including experience in laboratory record keeping, budget analysis and managing logistics. Knowledge of lab safety rules.

  • Proven experience in contributing and implementing innovative ideas and techniques on complex and multi-disciplinary research projects.

  • Proven ability to read scientific papers and adapt knowledge and techniques from the literature to experimental systems.

  • Excellent written, verbal and interpersonal communication skills including tack, diplomacy, and flexibility in order to work and interact effectively with staff, researchers, and management in person and on the phone.

  • Knowledge of PC software applications such as Word, Excel, Prism and PowerPoint to produce reports, correspondence, graphs, and spreadsheets to generate, track, and analyze data.


  • Experience with UCSD regulations, policies, and procedures.
  • Master's or Ph.D. degree.


  • Employment is subject to a criminal background check.
  • Must be willing to work with potentially hazardous materials such as radioactivity.
  • Must be willing to work extended hours.

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see:

UC San Diego is a smoke and tobacco free environment. Please visit for more information.

Application Instructions

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